A strong recommendation is one for which the panel is confident about the desirable effects over undesirable effects of the intervention, or other aspects, such as cost and feasibility.
The panel recommends a dose of LMWH 40 mg OD to LMWH 1 mg/Kg/OD SC, or Unfractionated Heparin 5000 U Q12H SC.
Definition of mild:
• Symptomatic (any acute COVID-19 related symptoms)
• AND respiratory rate <24/min
• WITHOUT pneumonia or hypoxia
A strong recommendation is one for which the panel is confident about the desirable effects over undesirable effects of the intervention, or other aspects, such as cost and feasibility.
The panel recommends a dose of LMWH 1 mg/Kg/BD SC.
Definition of moderate illness:
• Pneumonia (clinical or radiological) OR hypoxia (SpO2 <94% in adults with no underlying lung disease)
• AND respiratory rate ≤30/min
• AND SpO2 ≥90% on room air
Definition of Severe illness
Pneumonia with ANY ONE of the following:
• severe respiratory distress or respiratory rate >30/min
• SpO2 <90% on room air
• NO invasive or non-invasive respiratory support needed
A conditional recommendation is one for which the panel is less confident about the balance between desirable and undesirable effects of the intervention, or other aspects, such as cost and feasibility.
The panel recommends a dose of LMWH 1 mg/Kg/BD SC.
Definition of critical:
• Requirement for high-level respiratory support: noninvasive ventilation, high-flow oxygen (≥20 litres per minute) or invasive mechanical ventilation
• OR acute respiratory distress syndrome (PaO2/FiO2 ratio of <300)
• OR sepsis
• OR shock